Gene
slc6a3
- ID
- ZDB-GENE-010316-1
- Name
- solute carrier family 6 member 3
- Symbol
- slc6a3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have neurotransmitter:sodium symporter activity. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; nicotine dependence; and obesity. Is expressed in several structures, including dopaminergic neurons; forebrain; male organism; medulla oblongata; and retina. Orthologous to human SLC6A3 (solute carrier family 6 member 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 70 figures from 57 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| classic dopamine transporter deficiency syndrome | Alliance | Parkinsonism-dystonia, infantile, 1 | 613135 |
| {Nicotine dependence, protection against} | 188890 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sodium:neurotransmitter symporter | Sodium:neurotransmitter symporter superfamily |
|---|---|---|---|
|
UniProtKB:Q90ZV1
|
629 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc6a3-201
(1)
|
Ensembl | 1,890 nt |
Interactions and Pathways
No data available
Plasmids